From ElitistJerks:


PvE Mutilate, fast and flawed advice
Highest DPS dagger mainhand, have at least one fast dagger in either hand.
Fastest dagger - Deadly Poison, Other dagger - Instant Poison.

Priority:
* Ensure that there is a bleed (ie. Rupture, Deep Wounds, Rend) on the target.
* Start up Hunger for Blood.
* Start up Slice and Dice however you please, really.
* Use vanish whenever possible for Overkill buff.

1. Keep HFB up.
2. Keep SnD up (mainly via Envenom).
3. 4+ combo point Envenom.
4. ToT when off cooldown, especially with 2pc T10.



PvE Combat, fast and flawed advice
Mainhand a sword/axe, fist or mace weapon of generally slow speed.
Offhand a sword/axe, dagger or fist weapon of generally fast speed.
Mainhand Instant Poison, Offhand Deadly Poison.

Priority:
* Start up Slice and Dice however you please, really.
* Use cooldowns whenever possible. Killing spree + blade flurry, blade flurry +
adrenaline rush can be used. Adrenaline rush + killing spree is not recommended
due to energy capping.

1. Keep SnD up, no matter what the number of combo points are.
2. 5 point Eviscerate.
3. ToT when off cooldown, especially with 2pc T10