I have found, with a similar setup, the most effective to be as follows:
<----MAIN TOON---><-SUB1->
<-SUB2-><-SUB3-><-SUB4->
The main toon image takes up 2/3 width and 1/2 height of the screen. All the subscreens are pretty much square and take up 1/3 width and 1/2 height of the screen.
I used to stretch across the top like you, and also tried as per zanthor's suggestion, but with 1 screen I think this is best.
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