How did you set affinity to 15? If you did it through config.wtf file then it may be overidden by the virtual config file that ISboxer makes.
Try setting each client to use 4 cores in ISboxer itself. Each character should have a core selection for them.
Look at your virtual config files and make sure they are set right. Also look at task manager and make sure all all cores have a wow client(s).
Memory at 38% has me concerned. normally, 5 wow clients take up 6GB with OS. You are only using 3GB for load.
This is all I can think of for now.
Drommon
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