I run exactly the same system, 2 x intel ssds, GTX 295 slightly overclocked, 4GHz i7 920 12GB ram. As an aside, did you find it difficult pushing it to 4GHz with full memory banks? Took a fair bit of playing before mine ran stable with this using 7,7,7,20 1600MHz Patriot RAM.

The only difference is that I run all of my clients with ISboxer on a 30" dell.

At 2560 x 1600 on ultra in Dal I can't crack 30fps when running a single client. When I am running all 5 I keep Ultra settings on my main and turn shadows to simple. With this my main goes between 15 and 30fps generally. I find the draw distance makes a big difference in that if I am inside my fps will go to 45-60fps whereas if I am in the open it tends to drop fairly sharply.

So I am assuming it is the graphics limitations that cause the probs, rendering all of the frames. In highly populated AVs, I do not have this problem so it is obviously the polygon complexity in Dal as opposed to the older graphics zones. I am actually wondering if getting another GTX295 (or god forbid, 2 x 5970s) is worthwhile and using Innerspace to set "affinities" would improve frame rates.

Cheers