I ran Vista x64 for over a year, played copious amounts of games on it, and never remember it running like a slug. Just my experience.
I was thinking about hardware more in line for XP. I run Vista32 on a pretty powerful laptop and Vista64 on a very powerful desktop and they run fine. But when it was released, we got some laptops at work and it runs horrible on them, though XP runs just fine.
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