Blizzard doesn't care if the input is A, Shift A, Control A, Alt A, Alt+Shift (but not Control) A etc.
All that matters is one press = one action.

All of the FTL macro's or keymaps, can be accomplished in game.
If you can do it, with an in-game macro, and one press of a key or combination of keys results in one action, you're fine.