Haven't tried IS, which sounds cool, but for HKN and KC, keep in mind your slaves are rarely if ever standing directly on top of the leader. So no matter what you do with camera views, the mouse position on the leader window won't be the same for the slaves. I have experimented with passing the mouse with HKN and I just don't like it.
So just save a camera view zoomed in all the way, pointed straight down. Then no matter where you click (bound to a keystroke) you AOE right by you. I use this all the time for mage and lock AOE and also priest mass dispel. Works great, but you have to hit three keys. I have them (mostly) right next to each other and just roll three fingers across them.
One key to cast and setview, another to click, and a third to restore the view...
-K
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