Thanks for the clarification on mouse repeater regions.





For Eclipse, that is a different approach, but the same result.

With the keymap approach, I press my toggle (3rd keymap for a druid).
That disables a keymap, which is triggered by pressing 1 and sends the keybind for the IS/MF/Wrath click sequence.
It also enables a keymap, which is triggered by pressing 1 and sends the keybind for the IS/MF/Starfire click sequence.
I just need a toggle key for each druid, and an addon to announce Eclipse procs. Have the addon announce Druid A's ecplise as G7 and not Eclipse.

In the place of the toggle key, to enable one keymap and disable the other, I could go with a hotkey which swaps action bars.
I personally like the first solution better, since I have essentially unlimited keymaps within IS but a finite number of wow macro's.

In either case, I'm spamming the "1" key for my click sequence.
And sometimes it is doing IS/MF/Wrath and other times IS/MF/Starfire, all on the same spam key.