unbind the buttons part yeh need to unbind as in your example with 2 key every combo of shift ctrl alt plus the 2 that you use.
as in unbind
shift2
ctrl2
alt2
shiftctrl2 ...

you can use the /click command to get around the 255 char limit

or you can use macroon but yeh have to create a bar first the add buttons to it, the interface isnt all that intuitive.
Upper right hand corner on the mini map there's a circle that you have to right click on create a bar then click on the bar to add buttons. then right click on the lil circle to add a macro another time to bind it to a key.