I switched to IS boxer about 3 weeks ago and its simply amazing for multiboxing -- instant character switches were the reason I went but everything else is just perfect.

I actually use very few macros now since IS Boxer auto assist for everything so for shocks, lava burst, ect I just have the regular spell on the hotbar which makes switching to solo place a snap.

IS Boxer is to keyclone to what keyclone is to using no software.

It really is THAT good.