Castsequence macros are full of holes!

[SmartJelly]

E.g. if you have 3 buttons with:
/castsequence Flameshock,,,,,,,,,,,,,,,,,,,,,,,
/castsequence Lava Burst,,,,,,,,,,
/cast Ligthning Bolt
plus a spam macro to /click them in this order.

Actually, the commas are mostly used for timing.
As you noted,
/castsequence Lightning Bolt
/castsequence Flame Shock, Lava Burst

Off topic from the original post (but in keeping with the rest of it)... This would be a good example of how a comma sequence can be used to good effect to improve on the sequence below it. The Lightning Bolt is no longer on a cast sequence and won't be subject to any associated delays, and the fire spells can potentially be better timed to match their cooldowns.

yes thats why you use click macros

But does the use of 3 buttons and an additional /click provide any additional benefit beyond personal preference/macro size? It seems to me that the term "/click" has been associated with certain dps enhancements that aren't directly reliant on /click itself. Thus the notion of l2click is slightly misleading.