I changed from /castsequence using Light Bolt, Flame shock, and lava burst, to just plain lightning bolt and was really surprised, my pvp geared (season or 2 old) shaman went from about 1700dps to roughly 2200 just spamming lightning bolt instead (doesn't include heroism). I'll really have to try out the click macro stuff sometime and see how it goes. If i could get out of the AV xp grind soon :P

oh, and my latency is usually around 100 to 200 ms. So i'm not sure it's a huge factor, probably just the /castsequence command having delays in it for some reason.