Thanks for all the great advice - I can see that going with 3 sets of keys is a non-starter, I really need to nail down castsequence macros, that's something for me to read up on and play about with. The other part of macros I have been neglecting is the conditional macros so I need to get reading up on the expressions in the square brackets.

As far as team make up goes, from reading the replies and other threads on here it seems like almost any grouping can be made to function well (rogues and warriors are notably absent, rogues for obvious reasons, warriors as they have less AoE taunt than palladin I suspect).

I did try running 3 concurrent instances on a single PC last night (using the maximiser window program in keyclone) but it was very laggy - suspect RAM is the issue - so I will be purchasing another copy of keyclone and going to the 2 PC setup, time allowing this weekend too.

Thanks again for the helpful posts, really helped a newbie out/