I recently switched to Target=TargetTarget, as detailed in the "No Focus Manifesto".

Prior to moving to the Click Castsequences, my DPS spells on the spacegirls were similar to this:
#show Lava Burst
/cast [target=targettarget] [] Lava Burst

My Click castsequence dps macro on the spacegirls is:
#show Lava Burst
/Click MultiBarBottomRightButton9
/Click MultiBarBottomRightButton10

On MBBRB9, I have:
#show Lightning Bolt
/castsequence [target=targettarget] [] reset=8 Lightning Bolt,,,,,, (Comma's up to the 255 character limit)

On MBBRB10, I have:
#show
/castsequence [target=targettarget] [] reset=8 Flame Shock, Lava Burst, Lightning Bolt, Lightning Bolt, Lightning Bolt, Lava Burst, Lightning Bolt, Lightning Bolt, Lightning Bolt



When a spacegirl is targeting my pally, and the pally has a target, this works perfectly.
I get an initial Lightning Bolt, which because of the cast time is sufficient for my Pally to establish threat.
After that, each press goes through my FS, LvB, LB spam macro.

However, if the pally has no target or is out of range, the [] safety no longer works even though my Spacegirl has something targeted.

Anyone have any ideas?