I've got to disagree about the pain of a new team being macro's...

Thanks to ISBoxer I actually have very few macro's I use anymore, in fact I can only think of two offhand... my assist macro, and my mount macro, which is only a macro to save keyspace and not multibox related...

I can setup a new team in under 5 minutes if my UI's already configured for them... under 30 for brand new toons and thats all UI configuration, getting my chat box the right size, unit frames where I like them, etc... none of it's vital to multiboxing except the unitframe positions for click-heals.