Well I have been tweaking and I think I've got most of it finshed now to satisfaction.

Seems like running the monitors in horizontal span is, (as suggested in other posts) the best way for performance. It just stinks that I can't use my 22" with my main on it with the best resolution.

My only other question is how to use keyclone with a dual view set up, optimally, but that is a a question for the software forum.