what's the multisampling set to for each instance? I've got a core i7 920 with 12GB of fast ram, 30GB SSD (dedicated for wow), Asus 4850 and I was getting really crappy fps (5-7 in cities). I changed the video rez to 1x multisampling (down from 4x) on all my windows and reduced the view distance on all but my main and my FPS instantly shot up to 25-30 in dalaran and 60 everywhere else. just a thought ...