I thought Jamba had a feature to apply raid icons to mobs.
And another to make targetexact macro's on the fly.

So you can keybind apply skull icon.
And it will, on the fly, make a macro to targetexact the name of the mob you put the skull on.
You need to keybind apply each icon you use.
You need to keybind target the mob I marked.

It will probably break, if you're trying to target/mark four mobs of the same level with the same name.

I know Dot Timer can track damage to multiple different mobs.
But I don't think you can click anything to do with the addon to get Square as your target.