Nope. No way to target a mob without actually clicking on the mob. However, your character will automatically target the mob if the mob begins to attack you. This is why, at least so far in my playing experience, I have only come upon a bot once. The targetting mobs issue is probably the biggest hurdle, but there are also no commands for things like following another character. Instead, you must double click on them. The reason why this is so painful multiboxing is there is some weird inherent latency built into the game that makes keyboard/mouse repeating useless. I found that when I rotate the screen, each screen will be off even though they started with the exact same angle.

The reason why I thought people might know about multiboxing Perfect World was because I saw someone on the Innerspace forum post about launching multiple instances of Perfect World, so I had assumed that he was successful in figuring out macros for this game. I haven't been able to get in contact with him. The person's sn on Innerspace is bob_the_builder.