I agree with the above poster about both Keyclone and ISBoxer being very viable solutions. Both have tremendous support and are used by many so someone is always around to lend a hand if needed. I started with Keyclone and enjoyed using it thouroughly, and then I tried ISBoxer. At the time the PiP swap alone was enough for me to change, it really is instant. However having the ability to create and setup macros outside of Wow really was a bonus for me as well. I am sure the difference is negligable once you have everything setup, however that setup was smooth and quite enjoyable to do.

Good luck on your adventures! I know you will have a blast.