A very easy option for the slave is a simple macro:



/Targetlastenemy
/use Skinning(Master)

You need the (Rank) of skinning, be it Apprentice or what not.

If you fight three mobs at once, this will only skin the last.
If one is humanoid and two are animal, it will only skin the last mob, which might not be a legal skin target.
Still its a simple macro, which you can click very easily, one key press, to skin.

The interact with target is a very strong option for a lot of things.
Skinning works fine with that.
If I had not discovered the skinning macro, I would have just gone with the interact option.
Still interact depends on the main to target, the slave to assist and the slave to hit interact key.
But interact gets you a lot of things, opens quest guys on all toons, flight guys etc.