If you're used to an RP server make sure you move to an RP-PVP server not a normal PVP server. The normal PVP servers are full of asshats with stupid names like 'IPWNU' and the chat channels are non stop smack talk. At least on the RPPVP servers people who gank you aren't called 'Grieftoon'.
I think that group composition doesn't make much difference, go with something you're happy with rather than worrying about wether or not you'll be vulnerable to tactic x at level 80. All classes and races are useful but for multiboxing it's down to how easy you want to make it: 5 of the same class is always going to be easier than a mixed group but a mixed group should give you better synergy overall.
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