Tank + healer.

I do prot pally and holy priest. Easy peezy. I almost never die unless something stupid happens (which happens at least once a play session).

Things like the priest gets stuck on something and is out of LOS/range when I get massive aggro (I pull 10-20 mobs at once deliberately), or if they polymorph my pally and I can't get a dispel magic off fast enough before the priest is turned into pulp... That and mobs that shield-bash or spell interrupt. Lol. Okay so a few things can happen to make things "Go Wrong (TM)"