I have 5 WoW folders/setups. It is not ISBoxer causing this issue. I can open each client manually and as soon as I open the 3rd client I have no sound on that client while I still have sound on the first 2. I also can't hear on Ventrilo anymore after I open the 3rd client. As soon as I close the client, I can hear again. I disabled the sound on all but 1 client and still have the same issue. I am wondering if it just doesn't like my onboard sound. I really hate to go out and spend the money on a good sound card and end up having the same issue. That is why i am asking here first to get some sort of confirmation before I spend the money on a sound card.