No, I could do a /quit in wow outside an inn, not press any keys until it quits. The moment it quits keyclone would spike up in cpu (but not always stop responding at this point).
Standard settings I think, no mouse maps, maximiser for 2 monitors, 5 regions.
Memory usage stays the same at 8mb. 12gb ram on my machine.

Also, something else worth mentioning (I might have done in PMs at one point). My wow windows do not get removed from the keyclone window after I quit out of them.
Keyclone still shows 5 active wow windows even after I have quit all of them.