4v4 would be most similar to 2v2, as healer balance in 5s (normally 2 healer) is 40%, in 3s it's 33%, and in 2s it's 50%. Very few one healer teams would exist in a 4v4 environment seeing as two healers can already heal a 5v5 very well.
It would be the panultimate outlast bracket, where games would go to time more often than in 2v2. Cleave teams would also be more dominant in this bracket due to MS being so important (and with an MS class comes counter to offensive casters, so you might as well not even attempt to bring a warrior-warlock-healerx2 combo, for instance).
4v4 is a terrible idea. Sorry to crush everyone's dreams.
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