I've actually been 5-boxing with BOTH of these devices for a couple of months now, the Nostromo n52 (which I've actually had for a couple years now) and the Steelseries WoW Mouse which I just bought as soon as I was able to find one. Here's my thoughts:

The mouse itself is not a very well made device, physically. The button layout takes alot of getting used to, as does hand positioning. Also, after about a month and a half, the buttons started squeeking when I pushed them.

Now, those issues aside, this combo is F(*&ING AMAZING!!!!! Having those programmable buttons on the mouse is glorious!!!! I have it set up now between the two, I never have to touch the keyboard! I cant say enough good things about using these two together.

If I could ever find a better mouse with as many programmable buttons as the Steelseries WoW mouse, I would consider it, but right now, this is the best you can get, and I will NEVER go back to a standard 5-button mouse again!

Kalros - 80 Hunter
Grothan - 79 Paladin
Prothan - 75 Shaman
Drothan - 75 Shaman
Trothan - 75 Shaman
Crothan - 75 Shaman
Uther, son!