I decided to try something odd and took a lot of blood with my mostly unholy spec:

http://www.wowarmory.com/talent-calc...30101013103000

Adds a bunch of self healing with Rune Tap and Mark of Blood and gets as many mitigation and HP buffs as I could fit, while trying to grab all the AoE threat I could too.

Not sure if there is something I should sacrifice to get the extra point of Toughness, it's only 3% armor value.