I run on my main team, 2 destro warlocks, bm hunter, druid (heals) and pally (tank) and the first Boss is never an issue. I sometime use stun on the guys that weave the webs but mostly I just kill the Skirmishers first and then the rest of the adds. The boss himself is pretty much tank and spank, ignoring the little spider adds until after the boss is down.
Is your priest holy? From reading here, Discipline might be worth a shot for the extra survivability, nothing worse than losing the healer early in the fight

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