Don't know if this helps, but after a patch a few months ago I started having that problem.
In the end for me it appeared to be related to cpu. I was using the affinity to spread out usage over all four processors somewhat evenly and when they would all hit 100 usage plus read/writes I had problems. Now I always leave at least one processor with only one instance of how wow attached and I don't seem to have that issue anymore.
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