Allot of yer time is gonna be spent tweaking macros getting yer group working well together.
It aint easy unless you already have a good feel for the classes yer gonna be playing you will wipe quite q few times in instances.

Look into FTL setup I think that's about the most flexible setup yeh can get.

Yeh cant go wrong sticking to the tank/dps/healer group
There's allot of plus and minus with going a "mixed group" vs tank X4 same other classes.