I am interested in the same topic.

How do you fare with bosses that put an AoE damage debuff on you, like Ionar in HoL (just an example, there is plenty of others), that puts a spark on random party member, and it makes the nearby ones explode. With casters you just spread them, but with melee I have no idea. You just heal through the damage?

Also.. can you name a boss that is easier with melee than with casters? Not arguing here, just that can't think of one.