EQ2 requires all screens to be forced/locked into the forground...or to at least make it think they are in the forground.
I *think* Keyclone has an option for this, but I haven't attempted to use it with EQ2.

Innerspace with ISBoxer will work with EQ2 though (I'm using that now for it), and it will work on multiple computers.

There is more info on it here:
http://www.dual-boxing.com/mediawiki...p/Everquest_II