I ended up getting an OC'd GTX 280 last month, rather than a 285 or 295. My reasoning was that the card is clocked faster than any 285 I had seen (at the time) and was cheaper. Also, since there seems to be more reports of SLI not working with WoW rather than working better, I decided the 295 was not a good choice, especially if I can't just buy both and test each of them. I figured if I need SLI, I can just get another OC'd 280 (until they are no longer in stock). But I really don't play much of anything on my PC other than WoW.

I am using a 30" monitor with a Core 2 Q6600 and 8MB of RAM. I think the 280 runs very nicely. However, I am still CPU bound when running 4 clients. (with all graphics options except draw distance turned down) I just can't afford an i7 setup yet.