I use run 4 WoW's on my MacBok using ClonedKeys.
I run my main full screen also. (I like it and find it improves performance)
I've never experienced this problem though so I'm no help. I just wanted to let you know that it works for me. You can do it!
*I use a fubar addon (SwitcherFu) to full screen my main. Hitting Command-M will send that to both and WoW's and full screen them both at the same time. That may be causing a problem but it's just a guess.
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