Well doh umm I whould think that spanning causes problems with mouse placement, and puts a lot of strain on your video card. How you have it set up, main on one and 4 squares on the other? Does the mouse move seamlessly between the two monitors? I would see the main problem as that you must be playing in over 1900 X 1200 total on two monitors and the video card is really going to be working hard. Also whats the downside to using one? A single larger monitor seems better then two smaller anyways.

Well I don't know I guess I just use one monitor per computer and play always in full screen, I never liked the tile thing anyways. I just flip between my guys instead. If you don't have any problems then I guess I was wrong and 2 is fine, well basically I don't know.

Alwasy happy to share my wisdom lol ...