I'm hoping I'm just being dense and not seeing how this could be the issue, 'cause I want a fix ... but I don't think it's relevant. I'm using LALT (from the keymapping interface and the .kcl file itself, it seems your two choices are LALT and RALT), and basic ol' [mod:alt] in the macros. Definitely correct me if I'm wrong.

The weirdness is that Keyclone is either sending or receiving ALT-U for all the Moonfire hotstrings. SHIFT-CTRL-U becomes ALT-U, for example. This may not be exactly what's happening, but it *feels like using alt as the modifier on the primary key (alt-1) is overriding all the modifiers in the hotstring. Ctrl works properly. I don't know about shift as I don't use it in that macro.