Your question got me looking for external sata cases for more than one hard drive. It would be a good way to raid some fast drives without the internal space/heat/cable worry. There are quite a few of these items available and some of them have hardware raid controllers.

Last night I loaded my ssd in a thermaltake ext case I have. Fixing the drive in place could be an issue for you, depending on the case used, but I think a piece of tape would do the trick. There was sufficient friction on the power and data port to hold the drive during normal use but I could see the drive slipping during transport.

No testing on the E-Sata bus because I don't have the cable yet. I guess the best part of the external ssd is there is practically no heat or noise.

Good luck with your drive.