I think my computer just has trouble with 5 WoW instances open and switching between them takes a little time. I adjusted the mouseclick delays to 150 ms before and after, which seems click pretty reliably, but it's also 1.2 seconds to finish clicking my 4 slave screens.
May I ask your system spec, and if you run the 5 windows, so that they are all visible everytime or that some of them arent? (the later would explain why the ms are so high).
One question, would i need 5 wow folder
no, you don't need 5 folders, simply change the red-part in
<LaunchAndRename Local "C:\Users\Public\Games\WoW1\wow.exe" WoW1>
<LaunchAndRename Local "C:\Users\Public\Games\WoW2\wow.exe" WoW2>
<LaunchAndRename Local "C:\Users\Public\Games\WoW3\wow.exe" WoW3>
<LaunchAndRename Local "C:\Users\Public\Games\WoW4\wow.exe" WoW4>
<LaunchAndRename Local "C:\Users\Public\Games\WoW5\wow.exe" WoW5>
to the needed ones for your setup. As long as the names of the windows (the blue part) stay like they are here it should work.

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