Keyclone is great, its the easiest out of the box solution.
HKN I don't / have never used so I can't really comment.
IS + clickboxer / repeater / Windowsnapper is great. But it requires A LOT of DIY stuff. You can take stuff others have done and mod it to your needs but its still a pretty tough learning curve. The word is Lax is getting ready to test some stuff that makes setup MUCH easier. The only drawback I've seen so far with IS is the tough learning curve and setup.