Try removing the Logitech driver completely and use the MS default driver. If you have to use driver cleaner in safe mode to remove all the Logitech driver remnants. If mouse driving works fine with the default driver then get another download of the Mouseware and try it again. Frankly, on my gaming machine I don't use the logitech software except for the game panel of the G15.

A few other thoughts could be bios issues. I have no idea what to look for but poke around in the bios and see what is there. Maybe something will stand out and you will have an "aha!" moment.

Good luck.