I'm not a fan of Intel... maybe it's cause I work for DAAMIT ... Regardless, here's the Box I put together to 6-box EQ2. I know that WoW does need nearly this much power, but other games (fallout 3, crysis warhead) run flawlessly at the highest settings:

PSU CORSAIR|CMPSU-1000HX 1000W RT - Retail
MEM 2Gx4|GEIL GE28GB800C4QC R - Retail
CASE ANTEC|TWELVE HUNDRED BK RT - Retail
MB GIGABYTE GA-MA790GP-DS4H 790GX R - Retail
HD 1T|WD 7K 32M SATA2 WD1001FALS % - OEM (5 drives, Raid5 for gaming/storage) edit: *4 drives... too many numbers...*
HD 500G|WD WD5001AALS % - OEM (2 drives, raid0 for OS)
VGA SAPPHIRE 100259-1GL HD4870 1G R - Retail (two, with four monitors)
CPU COOLER ZALMAN|9700 LED RTL - Retail

I'm running an engineering sample processor, equivalent to the Phenom II x4 (3ghz core, 2ghz NB) which is unreleased at the moment (only the 1.8ghz NB version is available). I have the system overclocked to a 3.6ghz core, 2.4ghz NB & 2.4ghz HT3. The video cards are overclocked to 850 cpu / 1200mhz memory. I forced the memory to 4-4-4-15 CAS timings (Auto = 5-5-5-18 for some reason ). Everything is air cooled and ambient in-case temp during a dungeon run is < 60C. Idle temp is < 30C. It is power hungry due to the high NB... the Processor is probably pulling ~ 200Watts of power, but it's worth it.

There is one hitch... Some of the SATA connectors on the Mobo are covered up by the 2nd 4780 graphics card. The only way to get all 6 SATA connectors working is remove the connectors from the SATA Cables and carefully remove the connectors from the Mobo, then solder the SATA Cables directly onto the Mobo Pins. I don't recommend trying this unless you know what you're doing as your Warranties will be voided. However, it did work for me.

RD790 + SB750 is going to be the AMD Standard for 'enthusiast gaming' until the SB800 is released many moons from now. So, if you dont' like Intel or want to save some cash, I recommend this setup with the AMD Phenom II x4 940 (3ghz core, 1.8ghz NB).