Any chance to run the X-Keys without Macroworks running in the background?

I'm thinking about hardware-multiboxing 8)
- 5 PCs
- Vetra USB Multicaster
- X-Keys Pro 58 USB connected to the Multicaster

but I don't want to run any third party software
(so I don't want to have MacroWorks running while I'm playing).

Using MacroWorks for configuring the X-Keys is OK, but I'd like
to shut it down completely when I run Warcraft.

any chance to run the x-keys without the software?
or do I need to buy myself the PS/2 version again?