I used to use keyclone with my 5 druids on 2 PCs (lvl 71 now) but I got sick of having to start task manager every time to kill it. I switched to hkn and I really like it. With the help from this thread I got everything working very quickly. I find hkn easier to configure than keyclone and I like being able to make changes on the fly. I would like to point out that both programs have excellent customer support and both work fine for multiboxing. I am not bashing on keyclone.

Pros:
Load changes without restarting everything
More intuitive setup to start windows on remote computers
Wow windows seem to start up and shut down quicker
Window swapping seems to happen quicker (and is more reliable, I think in keyclone the main window needs focus when you hit your window swapping key but in hkn any window can have focus)
Program shuts down much quicker and does not stick around running in the background
Easy debugging, you can see what codes each key sends and you can see what actions happen when you press a key
FTL is easier to set up using the hkn templates than trying to enter them in the keyclone gui (I ended up writing a keyclone keymap generator in perl to make it easier)

Cons:
No nice gui like the keyclone one for designing your window layout
Does not restrict control to specified windows by default (takes over all keystrokes to all programs unlike keyclone, solution here: http://www.hotkeynet.com/phpBB3/view...7&p=5497#p5497)

Other thoughts:
Runaway toon problem happens in both keyclone and hkn for me.
I think people worry too much about resolution when designing a layout. From my testing it looks like it is best to let wow choose the right resolution based on the window dimensions. It does not seem to support odd resolutions although it is possible to create an ugly stretched window if you try.
I did not see a way in hkn to limit framerate (so now I don't think it is even necessary).
I did not try any mouse stuff in either program except I tried focus-follows-mouse in keyclone and did not like it (it is much slower focus switching than clicking).

-K