I have 2 buttons I press for my 5 box team: Pally, priest, druid, hunter, mage. Button one is my tank spam macro, my dps macros, and my healing macro. Button two is just tank threat and aggressive healing for when things go bad. I do have macros on several other buttons for other things but i can clear most instances with just those 2 buttons. Spend some time in the macros forum and all the sudden you find yourself being able to use special abilities on several classes effectively just by macroing them into something :thumbsup:

For example: My macro for boss pulls uses my arcane mage to pull while popping rage boosters for my druid tank and things like seal/judge on my ret pally, misdirect on my hunter etc.
Basically my mage hits his biggest single burst possible like arcane blast / POM 2nd arcane blast, my druid bumps up some rage and taunts off the mage before boss gets to him followed by misdirect from the hunter, judgements by the ret pally, big hits from the druid, Prayer of Mending from the priest.

All that is one button that I mash over and over for the first few seconds of a boss pull and the net result is a fully debuffed boss, huge threat lead for the tank, good damage done from the mage. I can pretty much coast through a boss after that. My goal with this complication is to raid with a 5 box of mixed classes in WotLK doing the tanking, healing, and some dps. My guild is impressed and they are going to give me a shot and we'll see how it goes when you add in the fight complexity of Naxx.