Sorry guys but you're not answering my question. I already know about using focus and [] to allow macros to function equally well when solo or multi.

I'm talking about having a _completely_ different setup for soloing - different keybinds, totally different macros, and fullscreen maxxed graphics as opposed to a 1024 window with min settings

i.e. The sort of thing you used to be able to do by having seperate installations of WoW for soloing and multiboxing