OK this is what happens with my f8-f12 buttons the macros are set as this when i hit them and swaps screens and is
/focus "new targets name"
/follow focus
/assist focus

That is the macro when they change. Then the macro for the spells are
/cast [target=focus target] lightning bolt

To me there seems like there should be more to it then just one line because when i switch screens the new main wants to target the old main who more then likely is a dead target and does not want to do anything but sit there but I'm going to try some more to resolve this problem and with help it might get done faster but i will see. And on the leaderless setup i have tried to understand it but i must still have my brain in the stone age lol.