I don't think so - not for now!
Maybe you can watch for every process launch, then patch user32.dll lol and detour setwindowshookex ... somehow. Otherwise I don't know of a way.
You still need a mouse hook when switched to a client, since RawInput is not gonna let you choke the mouse input. Plus, it is a bit slower so I use it only when I found neccessary :-)
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