I use the Skulltrail mobo... but the Asus is better.

The problem with the Skulltrail is that parts of it get REALLY hot. The memory controller and Nvidia SLI chip heat up and will overheat within 2 minutes if you don't have water cooling or a fan directly aimed at the mobo. I have a Vornado fan blasting air at my mobo whenever the pc is on.

Depending on how many instances of wow you want to run, the skulltrail is overkill and most of the machine cycles will go wasted.

I 5 box on the Skulltrail and my cpu usage never goes above 15%. So I run a VMWare window with CentOS in the background just to make myself feel useful

EDIT - I forgot to add that this motherboard is very afmoody. There's a high chance of it not posting after any hardware change like putting in memory or another video card. It's easy to get around, just short out the BIOS reset jumper, but I wasted hours of troubleshooting before figuring that out.