I get that problem too occasionally, usually on my 4th window, bottom right. Keyclone has a bug that tends to kick your cursor back to the main window or to the center of it as you cross the border or gap between instances. It seems that I get the spinnies when the cursor gets booted back while I'm clicking. If you could click in the spinning window (it's basically mouselook that's gotten stuck) you could stop it but your cursor always zaps back to main window.
Two things I do to fix it. One is I hit my follow macro, which focuses that little airhead back to following the party leader instead of playing My Little Dervish.
The other thing I do is hit my PiP swap to bring that spinning window to the main window and then click in it and regain control. Then I swap back.
edit: and as noted there are many ways to handle autofollows, the FTL searched above, zanthor's Hydra (if you search for that term it should come up) Zorba's Targat and Hold are all systems people use. Though I strongly recommend you go to the Macros and Addons forum here and get and read up on Jamba. I know it's a long long long thread but it's an incredibly useful tool for multiboxers. I've gone through and cut pasted all of the most useful posts from that thread into a word document, as my "manual" Can't recommend Jamba enough.
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